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SUMMARY OF THE INVENTION [0007] In one aspect of the invention, compounds are provided that inhibit KRas G12D activity. In certain embodiments, the compounds are represented by Formula (I): Formula (I) [0008] or a pharmaceutically acceptable salt thereof: [0009] wherein: [00010] R 1 is hydrogen, hydroxy, halogen, C1 – C3 alkyl, C1 - C3 ...

May 26, 2020 · Google Patents is a search platform with 120+ million patent dataset covering in 100+ jurisdiction that makes it one of the best available patent databases. April 24, 2024 +1-202-455-5058 [email protected] Data provided by IFI CLAIMS Patent Services. The present disclosure relates to the fields of packaging, transportation, and storage of temperature-sensitive materials, such as biological and/or pharmaceutical products. Various aspects of such packaging, transportation, and storage are provided herein for ultra-low temperature materials useful ...We would like to show you a description here but the site won’t allow us.Feb 27, 2024 · Google Patents is a free online search engine and database provided by Google that allows users to search and explore millions of patents from around the world. It provides access to a vast collection of patent documents, including granted patents, patent applications, and patent publications. Google Patents is useful in a wide range of ... Provided herein is a novel method of game play and game components that in one embodiment are in the form of trading cards (10, 12, 40, 42, 44, 48, 54, 60, 64). However, the game components may take other forms, such as a board game, or the game may be played in different media, such as electronic games, video games, computer games, and …What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the …an assay is used to determine whether the patient has KRas G12D mutation using a sample (e.g., a biological sample or a biopsy sample (e.g., a paraffin-embedded biopsy sample) from a patient (e.g., a patient suspected of having a KRas G12D-associated cancer, a patient having one or more symptoms of a KRas G12D-associated cancer, and/or a … Google Patents is a search engine from Google that indexes patents and patent applications from the United States Patent and Trademark Office, European Patent Office, and World Intellectual Property Organization. These documents include the entire collection of granted patents and published patent applications from each database.

UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857.US5025369A - Computer system - Google Patents Computer system Download PDF Info Publication number US5025369A ... 1988-08-25 Priority to US07/236,493 priority Critical patent/US5025369A/en 1988-08-25 Assigned to DAVID SCHWARTZ ENTERPRISES, INC., 73 EMMET AVE., EAST ROCKAWAY, NY A CORP.The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. The present disclosure further provides site-specific modifying polypeptides. The present disclosure further provides …The base plate, constituting the fundamental element of the brick, is generally designated by 1, the projections extending from one face of the base plate are hereinafter referred to as the primary projections 21, and the projections at the other face are referred to as the sec- 3,005,282 Patented Oct. 24, 1961 2 ondary projections 22.A method is provided for acquiring and transmitting biometric data (e.g., vital signs) of a user, where the data is analyzed to determine whether the user is suffering from a viral infection, such as COVID-19. The method includes using a pulse oximeter to acquire at least pulse and blood oxygen saturation percentage, which is transmitted ...Search and read the full text of patents from around the world with Google Patents, and find prior art in our index of non-patent literature.January 18, 2024. ⋅. 15 min read. 88. SHARES. 4.4K. READS. Reading and understanding patents filed by Google can be challenging but this guide will help you to understand …

Aug 1, 2023 · Google Patents. Google Inc. operates the Google search engine and the platform that delivers targeted ads to its users. The company also offers the GMail e-mail service, the Chrome web browser, the Google Play digital content store, as well as the Android mobile operating system. Jun 4, 2021 · Formula to generate search URLs. This file: Google spreadsheet 10. Filter search results. Lastly, on the search result page, you can apply different filters on the “Patent Office”, the ... The patent file contains at least one drawing executed in color. Copies of this patent with a color drawing will be provided by the Office upon request and payment of the necessary fee. FIG. 1 is a front view of a graphical user interface for a display screen or portion thereof showing our new design; and,Cite a patent issued to an inventor by a legal authority. Source type. Required. Title. Required. Container title. Contributors. Required. Add person.the RNA (e.g., mRNA) vaccineis a combination vaccine comprising a combination of any two or more of the foregoing vaccines. a methodfurther comprises administering to the subject a second (booster) dose of a RNA (e.g., mRNA) vaccine. Additional doses of a RNA (e.g., mRNA) vaccine may be administered.a further embodiment of the invention is a process for stabilizing ascorbic acid for storage, the process comprising combining 0.2% to 0.5% of a cinnamic acid derivative, such as p-coumaric acid, ferulic acid, caffeic acid, sinapinic acid, a derivative thereof, or a combination thereof; 10% to 60% of a solvent comprising a glycol ether and an alkanediol; and water; …

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Patent: A patent is a government license that gives the holder exclusive rights to a process, design or new invention for a designated period of time. Applications for patents are usually handled ...The present invention is based upon the isolation and identification of a new human Ebola virus species, EboBun. EboBun was isolated from the patients suffering from hemorrhagic fever in a recent outbreak in Uganda. The isolated virus is a member of the Filoviridae family, a family of negative sense RNA viruses. The invention provides for systems, methods, and compositions for altering expression of target gene sequences and related gene products. Provided are vectors and vector systems, some of which encode one or more components of a CRISPR complex, as well as methods for the design and use of such vectors. When we started Google Patents almost 10 years ago, our mission was to make patents more easily accessible. Today, we're announcing the addition of 11 more …

US4877027A - Hearing system - Google Patents Hearing system Download PDF Info Publication number US4877027A ... (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Expired - Lifetime Application number US07/202,679USD511342S1 2004-08-04 2005-11-08 High Tech Computer, Corp. Handheld electronic device. USD511347S1 2004-09-21 2005-11-08 Kabushiki Kaisha Toshiba Digital audio player. US20050255897A1 2004-04-29 2005-11-17 Samsung Electronics Co., Ltd. Double sliding-type portable communication apparatus. Google Patents is a search engine from Google that indexes patents and patent applications from the United States Patent and Trademark Office, European Patent Office, and World Intellectual Property Organization. These documents include the entire collection of granted patents and published patent applications from each database. Nov 30, 2023 · As part of this goal, Google has machine-annotated the worldwide patent corpus for scientific content and released the annotations publicly. The dataset includes billions of mentions of chemical compounds, diseases, proteins, genes, anatomy, etc, extracted from the full text, images, PDFs and translations of 130 million patents. Oct 3, 2022 · Additional advanced tip – Google Patents also includes the capability of searching non-patent literature using all the tips and tricks mentioned above. A user may simply select the “Scholar” look-alike logo to include the non-patent literature (the “Bulb” look-alike logo is to search the patent literature ). The principle of operation of the silent subliminal presentation system is as follows: An audio signal in the upper frequency region of the audio spectrum (for example, 14,500 Hz) is modulated with the desired information. The type of modulation may be any type suitable for subliminal applications; frequency modulation (FM), phase modulation ...Search and read the full text of patents from around the world with Google Patents, and find prior art in our index of non-patent literature.Apr 28, 2016 · As shown in FIG. 1, the craft 10 using an inertial mass reduction device comprises of an outer resonant cavity wall 100, an inner resonant cavity 200, and microwave emitters 300. The outer resonant cavity wall 100 and the inner resonant cavity wall 200 form a resonant cavity 150. The microwave emitters 300 create high frequency electromagnetic ...

A hand held, one touch jar opener can be placed on a jar and activated with a momentary touch of a button. An epicyclic gear train is set to sequentially provide a grip on a jar, and on a lid, followed by development of torque needed to move the lid in a counterclockwise direction with respect to the jar. The principles embodied in the opener shown can be …

UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857. Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1916-11-06 Filing date 1917-12-10 Publication date 1920-04-27 1916-02-27 Priority to GB2868/16A priority Critical patent/GB127289A/en Publication Publication Date Title. US6468525B1 2002-10-22 Probiotic formulation. TWI574633B 2017-03-21 Compositions comprising probiotic and prebiotic components and mineral salts, with lactoferrin. US8404228B2 2013-03-26 Food containing a probiotic and an isolated β-glucan and methods of use thereof.Google's most cited patents tend to revolve around search algorithms, data processing, and advertising technologies: 1. PageRank Algorithm: Although this was one of Google's …Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1953-04-10 Filing date 1954-04-09 Publication date 1957-10-15 ... In a Japanese patent application (application No. 1676/50, publicized on June 5, 1950) a process was described according to which a certain strain or ergot (Claviceps ...U.S. Provisional Patent Application No. 61/709,303 filed Oct. 3, 2012, entitled Modified Nucleoside, Nucleotide and Nucleic Acid Compositions, U.S. Provisional Patent Application No. exogenous unmodified nucleic acid …On August 13, 2010, Oracle sued Google for copyright and patent infringement in the District Court for the Northern District of California. Oracle asserted Google was aware that they had developed Android without a Java license and copied its APIs, and that Google therefore infringed Oracle's copyright.Mar 28, 2024 · What is Google Patents. Google Patents is Google's own patent search tool. It draws on patents from more than 100 of the biggest patent offices from around the world, enabling you to search across more than 120 million documents. As such it rivals the EPO's Espacenet for coverage. Full-text patent documents are indexed from 20 of the biggest ...

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Formula to generate search URLs. This file: Google spreadsheet 10. Filter search results. Lastly, on the search result page, you can apply different filters on the “Patent Office”, the ...Patent: A patent is a government license that gives the holder exclusive rights to a process, design or new invention for a designated period of time. Applications for patents are usually handled ... Search within the title, abstract, claims, or full patent document: You can restrict your search to a specific field using field names.. Use TI= to search in the title, AB= for the abstract, CL ... A method is provided for identifying and displaying video data of a user, either alone or together (in synchronization) with other data, such as biometric data acquired during a time that the video data was captured/received. The method includes storing biometric data separately from the video data, allowing the biometric data to be search quickly to …A slide-stopacuated by the magazine-follower to arrest the breech-slide in the open position when the magazine is empty,'has beenheretofore described and shown in the United States Patent- No. 708794, granted to me September 9, 1902, but the construction of the slide-stop as an integral part of the handle of the pivot-pin securing "the barrel and the breech … We would like to show you a description here but the site won’t allow us. Such a system and/or method could be used by an individual (e.g., athlete, etc.) or their trainer, coach, etc., to visualize the individual during the performance of an athletic event (e.g., jogging, biking, weightlifting, playing soccer, etc.) in real-time (live) or afterwards, together with the individual's concurrently measured biometric data (e.g., heart rate, etc.), and/or concurrently ... T NE 555 NITE- STATES ATENT' O FICE; SETH YVHEELER, OF ALBANY, NEYV YORK. WRAPPING OR `TOILET PAPER ROLL. SPECIFICATION forming part of Letters Patent No. 459516, dated September 15, 1891, Application filed June 10. 1891.Global Dossier. Patent Application Information Retrieval (PAIR) Public Search Facility. Patent and Trademark Resource Centers (PTRCs) Patent Official …LOT Network Launched in 2014 by Canon, Google, Red Hat and others, LOT Network administers an industry-led, networked, royalty-free patent cross license agreement affecting patents transferred to ... ….

Google Patents, a patent search engine created by Google, includes over 120 million patent publications from 100+ patent offices around the world, as well as many technical …We would like to show you a description here but the site won’t allow us.We would like to show you a description here but the site won’t allow us.The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell … FIELD OF THE INVENTION. The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease. BACKGROUND TO THE INVENTION. The device of claim 1, further comprising a compressed gas source within the container and piped to release compressed gas within the mosquito breeding bin. US14/549,3052014-11-202014-11-20Toxic mosquito aerial release system ActiveUS8967029B1(en) Priority Applications (1) Application Number.A hand held, one touch jar opener can be placed on a jar and activated with a momentary touch of a button. An epicyclic gear train is set to sequentially provide a grip on a jar, and on a lid, followed by development of torque needed to move the lid in a counterclockwise direction with respect to the jar. The principles embodied in the opener shown can be …A system for generating three-dimensional objects by creating a cross-sectional pattern of the object to be formed at a selected surface of a fluid medium capable of altering its physical state in response to appropriate synergistic stimulation by impinging radiation, particle bombardment or chemical reaction, successive adjacent laminae, representing … Patent google patent, US8983682B1 * 2012-12-28 2015-03-17 Google Inc. Unlocking mobile-device and/or unmanned aerial vehicle capability in an emergency situation. US9051043B1 * 2012-12-28 2015-06-09 Google Inc. Providing emergency medical services using unmanned aerial vehicles. USD741751S1 * 2014-12-11 2015-10-27 SenseFly Ltd. Drone., Data provided by IFI CLAIMS Patent Services. A method for administration of ibuprofen to a subject in need of ibuprofen treatment is provided, in which an oral dosage form comprising a therapeutically effective amount of ibuprofen and a therapeutically effective amount of famotidine is administered three times per day., 2005-08-01 FPAY Fee payment. Year of fee payment: 12. The invention provides improved methods for assaying samples for the presence of a beetle luciferase. The methods of the invention entail improved kinetics of light production from luciferase activity in beetle luciferase-luciferin reactions., Example 3 of said patent discloses that 18 PPM of said crystal devices could totally suppress the AIDS virus (page 6, line 5). Subsequent to the filing of the aforementioned patent, further testing revealed complete 100% destruction of the AIDS virus in vitro at 20 PPM, and the fact that said devices were harmless when ingested and inhaled ... , The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. , The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …, About Google Patents. Overview. Search and read the full text of patents from around the world. Next: Coverage. Patents from around the world, translated. Plus technical papers …, the RNA (e.g., mRNA) vaccineis a combination vaccine comprising a combination of any two or more of the foregoing vaccines. a methodfurther comprises administering to the subject a second (booster) dose of a RNA (e.g., mRNA) vaccine. Additional doses of a RNA (e.g., mRNA) vaccine may be administered., We would like to show you a description here but the site won’t allow us., Google patents database is built using patents from 17 patent offices* around the world. The database contains over 87 million patent publications including. Search Techniques. You can directly type text in the search bar. The search engine splits search strings and searches individual keywords in the search string., Opens Google Patents for a selected patent identifier. This solution allows you to quickly open Google Patents for a selected patent identifier. Select a patent identifier in text, then open the context menu and select "Open Google Patents" from the menu. You can normally open the context menu by right-clicking., FIELD OF THE INVENTION. The present invention relates to an attenuated coronavirus comprising a variant replicase gene, which causes the virus to have reduced pathogenicity. The present invention also relates to the use of such a coronavirus in a vaccine to prevent and/or treat a disease. BACKGROUND TO THE INVENTION. , The present invention relates to liquid pharmaceutical compositions comprising the GLP-1 peptide semaglutide and no more than 0.01% (w/w) phenol. Surprisingly, the present inventors found that such compositions have improved chemical and/or physical stability. In some embodiments the composition comprises no phenol., US7955605B2 - Multivalent pneumococcal polysaccharide-protein conjugate composition - Google Patents Multivalent pneumococcal polysaccharide-protein conjugate composition Download PDF Info Publication number ... as described in International Patent Application WO2004/083251 [38]), E. coli LT, E. coli ST, and exotoxin A from Pseudomonas …, The present invention relates generally to the field of human genetics. Specifically, the present invention relates to methods and materials used to isolate and detect a human breast and ovarian cancer predisposing gene (BRCA1), some mutant alleles of which cause susceptibility to cancer, in particular breast and ovarian cancer. More specifically, the …, Such a system and/or method could be used by an individual (e.g., athlete, etc.) or their trainer, coach, etc., to visualize the individual during the performance of an athletic event (e.g., jogging, biking, weightlifting, playing soccer, etc.) in real-time (live) or afterwards, together with the individual's concurrently measured biometric data (e.g., heart rate, etc.), and/or concurrently ... , Description. Claims (79) Hide Dependent. The invention relates to a wheelchair for example a wheelchair for an active user, a method of manufacturing a wheelchair and a wheel for a wheelchair. In further aspects the invention relates to a wheelchair, a footrest for a wheelchair, a wheelchair having a light, and a seat back for a wheelchair, a ..., Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 2020-08-11 Filing date 2020-11-30 Publication date 2021-08-31 2020-08-11 Priority claimed from IL276665A external-priority patent/IL276665A/en 2020-08-11 Priority claimed from IL276648A external-priority patent/IL276648A/en , WW/LGOOGO fhweutoz we umloxu. umcmm wm co: AAAAAA v, UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEIV YORK, N. Y. ELECTRIC G EN ERATO R. SPECIFICATION forming part of Letters Patent No. 511,916, dated January 2, 1894. Application filed August 19,1893., Google will consider licensing offers for granted patents. If you do not have a patent but only a business idea, please do not make a submission as we will not consider non …, UNITED STATES PATENT OFFICE. NIKOLA TESLA, OF NEW YORK, N. Y., ASSIGNOB O F ONE-HALF TO CHARLES F. PECK, OF ENGLEWOOD, NEW JERSEY. ELECTRO-MAGN-ETIC MOTOR. SPECIFICATION forming part of Letters Patent No. 381.968, dated May-1, 1888. Application filed October 12. 1857., USPTO’s new Diversity Information Platform: Advancing innovation through data-driven action. The unique online platform is free and available to anyone with an internet connection. Home page of the United States Patent and …, The present invention describes a liquid injectable composition comprising acetaminophen, hydroxyethylstarch and at least one osmolality agent. Further, the invention relates to a pharmaceutical composition for the prophylaxis and treatment of pain and fever containing said injectable composition. Additionally, the invention relates to a process for the …, Publication Publication Date Title. US1773079A 1930-08-12 Method of preparing food products. US1810864A 1931-06-16 Process for the production of food product bricks. US2286644A 1942-06-16 Method and apparatus for processing potatoes. US1998431A 1935-04-23 Method and apparatus for freezing food products., The present disclosure provides a DNA-targeting RNA that comprises a targeting sequence and, together with a modifying polypeptide, provides for site-specific modification of a target DNA and/or a polypeptide associated with the target DNA. , The present disclosure relates to the field of vaccines and binding molecules, as well as preparations and methods of their use in the treatment and/or prevention of disease. Described are vaccines and binding molecules, compositions containing the same, and uses thereof for treating or preventing coronavirus infections, in particular, β …, USPTO’s new Diversity Information Platform: Advancing innovation through data-driven action. The unique online platform is free and available to anyone with an internet connection. Home page of the United States Patent and …, Apr 28, 2016 · As shown in FIG. 1, the craft 10 using an inertial mass reduction device comprises of an outer resonant cavity wall 100, an inner resonant cavity 200, and microwave emitters 300. The outer resonant cavity wall 100 and the inner resonant cavity wall 200 form a resonant cavity 150. The microwave emitters 300 create high frequency electromagnetic ... , , To cite a patent in APA Style, list the name of the inventor, the year it was issued (in parentheses), the title of the patent (in italics), the patent number, the name of the issuing body, and the URL if available. Our free APA Citation Generator can help you create accurate citations quickly and easily. Inventor name, Initials. ( Year )., Opens Google Patents for a selected patent identifier. This solution allows you to quickly open Google Patents for a selected patent identifier. Select a patent identifier in text, then open the context menu and select "Open Google Patents" from the menu. You can normally open the context menu by right-clicking., Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) 1996-12-13 Filing date 2002-04-24 Publication date 2003-07-01 ... 2002-09-05 Publication of US20020123775A1 publication Critical patent/US20020123775A1/en 2003-07-01 Application granted granted Critical, The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell culture media, including improved production media, feed solutions, and combination feeds, which may be used to improve protein productivity in mammalian cell …