Methocarbamol vs cyclobenzaprine

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In Robaxin vs Flexeril, both of the drugs’ primary use is for the treatment of muscle spasms and pain. However, the former can also be used as a relief from tetanus spasms. Additionally, in Methocarbamol vs Flexeril (Cyclobenzaprine), both prescription medications come in generic forms. Robaxin vs Flexeril comparison is one of the most ...Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dantrolene compared to placebo in patients with musculoskeletal conditions.Robaxin vs Flexeril Robaxin. Mostly known by its generic name of methocarbamol, Robaxin has been around for decades, dating back to the 1960s. Although its exact components are generally unknown, it’s used mostly to relieve an individual of various bouts of discomfort.Methocarbamol and Cyclobenzaprine are both muscle relaxant medications used to treat muscle spasms. However, they have different mechanisms of action. Methocarbamol depresses the central nervous system, while Cyclobenzaprine is structurally related to tricyclic antidepressants and has a sedative effect. …Learn about the differences between methocarbamol (Robaxin) and cyclobenzaprine (Fexmid, Amrix), two skeletal muscle relaxants used to treat muscle pain and spasms. Find out how they …More about Metaxalone. Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Metaxalone has an average rating of 7.2 out of 10 from a total of 127 ratings on Drugs.com. 60% of reviewers reported a ...

Metaxalone has an average rating of 7.2 out of 10 from a total of 127 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 18% reported a negative effect. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative ...More about Zanaflex ( tizanidine ) Ratings & Reviews. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers ...There's nothing terribly exciting to speak of in today's Firefox 3.5.5 update; from the looks of the tiny changelog, it looks like one critical security fix and a few other minor b...This article reviews the etiologies and treatment options for spasticity and spasm, 2 conditions that affect skeletal muscle excitability and contraction. It does not … Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dantrolene compared to placebo in patients with musculoskeletal conditions. Cyclobenzaprine is available as 5-mg and 10-mg immediate-release tablets and 15-mg and 30-mg extended-release tablets. 34, 37 The current recommended dosing regimen starts at 5 mg three times daily (10 mg at bedtime for fibromyalgia), and can be titrated to a maximum dose of 10 mg three times daily. 34 The initial dose of the extended-release ...

What is the difference between flexeril and robaxin (methocarbamol)? A Verified Doctor answered. Physical Medicine and Rehabilitation 25 years experience. Muscle relaxants: Flexeril ( cyclobenzaprine hcl) tends to cause more sedation and is a stronger muscle relaxant. Created for people with ongoing healthcare needs but benefits everyone.The best prescription muscle relaxants are baclofen, carisoprodol, methocarbamol, tizanidine, dantrolene, cyclobenzaprine, orphenadrine, chlorzoxazone, and metaxalone. Naproxen (Aleve) is one of the strongest OTC medications for muscle pain, cramps, and spasms. One skeletal muscle relaxant may not be better than the …You can fly from cities on the East and West Coast to Japan for cheap! Update: Some offers mentioned below are no longer available. View the current offers here. Want to see the la...Cyclobenzaprine is FDA-approved as an adjunct to rest for the treatment of muscle spasms associated with acute, painful musculoskeletal conditions. Cyclobenzaprine is a part of a group of medications referred to as cyclical antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant …

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Boom Supersonic continues to set itself apart: its Overture airliner will be propelled by brand-new engines the company just revealed. Boom Supersonic is working hard to upend the ...The sedative properties of tizanidine and cyclobenzaprine may benefit patients with insomnia caused by severe muscle spasms. Methocarbamol and metaxalone are less sedating, although effectiveness evidence is limited. Adverse effects, particularly dizziness and drowsiness, are consistently reported with all skeletal muscle relaxants. Reply.Descriptions. Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem.Introduction. Pain from fibromyalgia can have a severe impact on your quality of life, making even normal tasks difficult. Two muscle relaxants called Zanaflex and Flexeril are among the drugs ...Sep 21, 2021 · Robaxin vs flexeril are similar medicines used for muscle relaxing. The differences lie in their active ingredient, price, area of most effect and others. The generic name for Robaxin is Methocarbamol and Cyclobenzaprine is the generic name of Flexeril. Robaxin and Flexeril are both effective treatments for musculoskeletal pain and muscle ... Baclofen has an average rating of 7.0 out of 10 from a total of 435 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect.

Comparison studies have not shown one skeletal muscle relaxant to be superior to another. Cyclobenzaprine is the most heavily studied and has been shown to be effective for …Feb 29, 2024 · Methocarbamol is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury. Methocarbamol injection is sometimes used in the treatment of tetanus, (lockjaw) which causes painful tightening of the muscles. Warnings. You should not use this medication if you are allergic to methocarbamol. Oct 1, 2022 · People with liver disease should avoid tizanidine, and those with kidney disease should take baclofen in lower doses. Also, avoid the drugs carisoprodol (Soma), chlorzoxazone (generic only), cyclobenzaprine (Amrix), metaxalone (Metaxall), methocarbamol (Robaxin), and orphena-drine (generic only) because of their risk for drowsiness and falls. Possible Side Effects and Risks. As with all drugs, muscle relaxers can cause side effects. The one possible side effect common to all muscle relaxers is dizziness and drowsiness, although some cause greater drowsiness than others. Common side effects of muscle relaxants (by drug class) include: Benzodiazepines. Drowsiness.Cyclobenzaprine is FDA-approved as an adjunct to rest for the treatment of muscle spasms associated with acute, painful musculoskeletal conditions. Cyclobenzaprine is a part of a group of medications referred to as cyclical antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant …Jul 26, 2021 · Methocarbamol (Robaxin) is an oral medication used to treat muscle pain and stiffness. Learn about side effects, warnings, dosage, and more. In Robaxin vs Flexeril, both of the drugs’ primary use is for the treatment of muscle spasms and pain. However, the former can also be used as a relief from tetanus spasms. Additionally, in Methocarbamol vs Flexeril (Cyclobenzaprine), both prescription medications come in generic forms. Robaxin vs Flexeril comparison is one of the most ...ulti001. • 3 yr. ago. Baclofen and tizanidine are the only two drugs FDA approved for muscle spasticity. Often times the selection will depend on the mechanism of action/Side effect profile in the underlying ailment. For instance cyclobenzaprine may be more appropriate in somebody with muscle issues and some type of neuropathy.Jul 22, 2022 ... The skeletal muscle relaxants (SMRs), carisoprodol, chlorzoxazone, cyclobenzaprine, methocarbamol, metaxalone, and orphenadrine, are FDA ...Whether you're planning backyard cookouts, camping trips in the woods, or long and sunny beach days, these Costco items will get you ready for the season. We may receive compen...Both Methocarbamol and Cyclobenzaprine are effective muscle relaxants that provide relief from pain and muscle spasms. Methocarbamol works by depressing the central nervous system, which helps to relax the muscles. Cyclobenzaprine, on the other hand, works by blocking nerve impulses or pain sensations that are sent to the brain.

Side Effects. Drowsiness, dizziness, lightheadedness, stomach upset, nausea / vomiting, or blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist ...

Nov 18, 2010 ... The SMRs investigated were baclofen, cyclobenzaprine, dantrolene, methocarbamol, orphenadrine, and tizanidine. Baclofen is indicated in the ...Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dantrolene compared to placebo in patients with musculoskeletal conditions.A world-record nonstop from Austria to Australia, medical-emergency flights in vintage jets, and more ways that airlines are getting creative in a world changed by the virus. The o...Methocarbamol and Cyclobenzaprine are both muscle relaxant medications used to treat muscle spasms. However, they have different mechanisms of action. Methocarbamol depresses the central nervous system, while Cyclobenzaprine is structurally related to tricyclic antidepressants and has a sedative effect. Cyclobenzaprine 10 Mg Vs Methocarbamol ...Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... more. Prescription only. Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation.A comparison of cyclobenzaprine and methocarbamol, two skeletal muscle relaxants for acute and chronic pain, based on their advantages, …Marriage counselors can help you effectively communicate with your partner. But if your spouse won't go to marriage counseling, other options are available. If your spouse won’t go...Jul 24, 2017 ... NNT for substantial pain relief was about 6-7 by day 4. One double-blind crossover trial in fibromyalgia compared cyclobenzaprine 10 mg daily at ...The following are some of the most common alternatives to methocarbamol. 1. Amrix or Fexmid (cyclobenzaprine) Amrix and Fexmid are the brand names of a medication called cyclobenzaprine. Like methocarbamol, cyclobenzaprine is a muscle relaxant used for muscle spasms and pain. Cyclobenzaprine is the most heavily …

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Flexeril or Amrix (cyclobenzaprine): Cyclobenzaprine is a popular and relatively inexpensive generic muscle relaxant often used short-term to treat muscle spasms and pain related to sprains, strains, etc. A typical dose is five to 10 mg at bedtime for two to three weeks, although your doctor might approve up to 30 mg daily (taken as one 5 or 10 ...Feb 25, 2020 · Q: Which muscle relaxer is the strongest? There are several muscle relaxers, or skeletal muscle relaxants. They include cyclobenzaprine (Flexeril), methocarbamol (Robaxin), and tizanidine (Zanaflex), among others. According to the American Academy of Family Physicians, there is no clear evidence that one is better or stronger than another. Robaxin (methocarbamol) Robaxin is commonly used to treat severe muscle spasms, back pain, and occasionally tetanus spasms. It's an injection which typically costs about $160 per 2, 10 mL of 1000 mg/10 mL solution without insurance. Norflex (orphenadrine) Norflex has been discontinued in the U.S.Applies to: doxepin and cyclobenzaprine. Using doxepin together with cyclobenzaprine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking ...Descriptions. Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem.Whether you're planning backyard cookouts, camping trips in the woods, or long and sunny beach days, these Costco items will get you ready for the season. We may receive compen...Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Diazepam has an average rating of 8.5 out of 10 from a total of 858 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 9% reported a negative ...Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... more. Prescription only. Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. cyclobenzaprine, tizanidine, carisoprodol, metaxolone, and methocarbamol among others (1,2). While the mechanism for most of these agents is unclear, they are all central nervous system depressants and their effect may be related to sedation. Cyclobenzoprine (flexeril) is related to tricyclic antidepressants. ….

cyclobenzaprine, tizanidine, carisoprodol, metaxolone, and methocarbamol among others (1,2). While the mechanism for most of these agents is unclear, they are all central nervous system depressants and their effect may be related to sedation. Cyclobenzoprine (flexeril) is related to tricyclic antidepressants.Side effects of Zanaflex that are different from Robaxin include anxiousness, nervousness, numbness or tingling, stomach pain, diarrhea, fever, dry mouth, muscle weakness, back pain, increased muscle tone or spasms, sweating, and fatigue. Both Robaxin and Zanaflex may interact with alcohol or other drugs that make you sleepy or slow your ...Methocarbamol and Flexeril are both muscle relaxants, but they have different mechanisms of action. Methocarbamol works by depressing the central nervous system, which results in muscle relaxation. Flexeril, on the other hand, works by blocking nerve impulses that are sent to the brain, which can help to reduce muscle spasms and pain. When it ...Methocarbamol - forgetfulness, allergic reactions, being anxious, blurred vision, a slow heart rate, being confused or dizzy, headache, heartburn, feeling or being sick, itching, rash, and low blood pressure. Cannabis extract - feeling dizzy, depressed mood, diarrhoea or constipation, mouth ulcers or pain, feeling tired or sick, appetite ...Flexeril, Amrix, and Fexmid are brand names of this drug in the U.S. Cyclobenzaprine comes in two oral forms: immediate-release tablets and extended-release capsules. ... Methocarbamol ...Metaxalone has an average rating of 7.2 out of 10 from a total of 127 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 18% reported a negative effect. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative ...Cyclobenzaprine PO: 5-10mg TID • Caution in age ≥65 (reduce dose or avoid) • Causes dizziness, somnolence • Tizanidine: causes hypotension • Consider limiting to 14 day duration Methocarbamol PO: 500-1000mg TID Tizanidine PO: 2mg TID to maximum dose of 36mg/day Gabapentinoids Gabapentin PO: 300-3600mg/dayTaken as needed, 1500 mg every 6 to 8 hours is a cheap and well-tolerated option for sufferers of acute neck and back pain. Think of trying this first, as it is less sedating than other options, like cyclobenzaprine and carisoprodol. 2) Cyclobenzaprine (Flexeril) At the standard dose of 10 mg to 30 mg a day, cyclobenzaprine will make you sleepy ... Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative ... Comparing Methocarbamol vs Cyclobenzaprine: Methocarbamol and cyclobenzaprine are examples of muscle relaxants that are used to treat... Skip to content Free 24-Hour Addiction Support Hotline Open During COVID-19 w/Safety Protocols Methocarbamol vs cyclobenzaprine, IMS Health data from 2003–2004 showed carisoprodol, cyclobenzaprine, and metaxalone accounted for more than 45% of all prescriptions written for the …, A pill imprinted with “V” on one side and 2632 on the other indicates cyclobenzaprine hydrochloride, according to Drugs.com. The pill is most commonly used to treat muscle spasms., Comparing Methocarbamol vs Cyclobenzaprine: Methocarbamol and cyclobenzaprine are examples of muscle relaxants that are used to treat... Skip to content Free 24-Hour Addiction Support Hotline Open During COVID-19 w/Safety Protocols, What is the difference between flexeril and robaxin (methocarbamol)? A Verified Doctor answered. Physical Medicine and Rehabilitation 25 years experience. Muscle relaxants: Flexeril ( cyclobenzaprine hcl) tends to cause more sedation and is a stronger muscle relaxant. Created for people with ongoing healthcare needs but benefits everyone., This medication primarily targets the alpha motor neurons in the spinal cord, which are responsible for regulating muscle tone. By modulating these neurons, Flexeril alleviates muscle spasms and enhances mobility, providing relief to individuals grappling with musculoskeletal discomfort. On the other hand, Robaxin, or methocarbamol, functions ..., Comparing Methocarbamol vs Cyclobenzaprine: Methocarbamol and cyclobenzaprine are examples of muscle relaxants that are used to treat... Skip to content Free 24-Hour Addiction Support Hotline Open During COVID-19 w/Safety Protocols, Dantrolene. Dantrolene (Dantrium) is a skeletal muscle relaxer used to treat muscle spasms caused by spinal cord injury, stroke, cerebral palsy, or MS. It works by acting directly on the skeletal ..., oxycodone/acetaminophen vs. cyclobenzaprine was 0.9 (98.3% CI, -2.1 to 3.9; p=0.45). They concluded ... of methocarbamol vs. placebo in patients with acute musculoskeletal pain and spasm from traumatic or inflammatory conditions . A total of 180 patients were randomized into either placebo or treatment(6), Cyclobenzaprine is available as 5-mg and 10-mg immediate-release tablets and 15-mg and 30-mg extended-release tablets. 34, 37 The current recommended dosing regimen starts at 5 mg three times daily (10 mg at bedtime for fibromyalgia), and can be titrated to a maximum dose of 10 mg three times daily. 34 The initial dose of the extended-release ..., methocarbamol food. Applies to: methocarbamol. Alcohol can increase the nervous system side effects of methocarbamol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with methocarbamol., Apr 15, 2024 · Methocarbamol is taken by mouth, typically 3 or 4 times daily. It's also available as an injection that's given into the muscles or through the veins, typically in a hospital setting. Side effects of methocarbamol include dizziness, drowsiness, and blurry vision. Reviewed by: Robert Chad Hakim, PharmD, BCCCP. Allison Gourley, PharmD. , A comparison of cyclobenzaprine and methocarbamol, two skeletal muscle relaxants for acute and chronic pain, based on their advantages, …, Methocarbamol (Robaxin) is an oral medication used to treat muscle pain and stiffness. Learn about side effects, warnings, dosage, and more., More about Flexeril ( cyclobenzaprine ) Ratings & Reviews. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 13% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers ..., Cyclobenzaprine is a muscle relaxant that may be used short-term to treat muscle spasms caused by musculoskeletal conditions, in addition to rest and physical therapy. Sedation is a common side... more. Prescription only. Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation., Short-term symptomatic relief of muscle spasm. By mouth. Adult. 1.5 g 4 times a day; reduced to 750 mg 3 times a day if required. Elderly. Up to 750 mg 4 times a day, dose may be sufficient., Robaxin and Flexeril are both muscle relaxants but work in different ways. Compare the side effects and cost of these drugs to find out which one is better. Drug vs. Drug. Robaxin vs. Soma: Differences, similarities, and which is better for you., Methocarbamol is used to treat acute pain, strains, injuries, discomfort, ligaments pains, etc. Cyclobenzaprine directs work on skeletal muscle, and Methocarbamol works on CNS (Central Nervous system) to stop pain receptors. If required, you may be prescribed both the drugs together. Overall these two drugs do not interact …, Robaxin (methocarbamol) and Flexeril (cyclobenzaprine) are muscle relaxants used to treat skeletal muscle conditions. Learn about their common and serious side effects, drug interactions, and how to take them safely., Dosage for relief of muscle spasms. Adult dosage (ages 18–64 years) 5–10 mg taken 3 times per day. Child dosage (ages 15–17 years) 5–10 mg taken 3 times per day. Child dosage (ages 0–14 ..., More about Flexeril ( cyclobenzaprine ) Ratings & Reviews. Tizanidine has an average rating of 6.1 out of 10 from a total of 377 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 30% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers ..., It takes bravery to end a marriage, and that bravery is worth celebrating. A divorce is typically an emotionally draining and difficult process that’s rife with negativity. But som..., cyclobenzaprine, Flexeril. diazepam, Valium. metaxalone, Skelaxin. methocarbamol, Robaxin. How It Works. The muscle-relaxing effects of these medicines are most ..., More about Zanaflex ( tizanidine ) Ratings & Reviews. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers ..., More about Valium ( diazepam ) Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Valium has an average rating of 8.7 out of 10 from a total of 336 ratings on Drugs.com. 86% of reviewers reported a ..., Objective To investigate the efficacy, acceptability, and safety of muscle relaxants for low back pain. Design Systematic review and meta-analysis of randomised controlled trials. Data sources Medline, Embase, CINAHL, CENTRAL, ClinicalTrials.gov, clinicialtrialsregister.eu, and WHO ICTRP from inception to 23 February 2021. Eligibility …, Gabapentin is an anticonvulsive medication that is primarily used to treat seizures and nerve pain. It was initially developed as a muscle relaxer and anti-spasmodic medication, but its anticonvulsive properties were discovered later. Gabapentin is also used as an adjunct to more potent anticonvulsants and for the management of certain types of ..., Possible Side Effects and Risks. As with all drugs, muscle relaxers can cause side effects. The one possible side effect common to all muscle relaxers is dizziness and drowsiness, although some cause greater drowsiness than others. Common side effects of muscle relaxants (by drug class) include: Benzodiazepines. Drowsiness., Few differences : Both Methocarbamol ( robaxin) and flexaril( cyclobenzaprine) are muscle relaxants. Exact mechanism of action is unknown, but both are most probably centrally acting muscle relaxants. Robaxin (methocarbamol) has a short half life of 1-2 hrs. And is usually given 4 times a day. Flexeril's half life is 18 hrs (range of 8-37 hrs ..., Oct 25, 2023 · Flexeril or Amrix (cyclobenzaprine): Cyclobenzaprine is a popular and relatively inexpensive generic muscle relaxant often used short-term to treat muscle spasms and pain related to sprains, strains, etc. A typical dose is five to 10 mg at bedtime for two to three weeks, although your doctor might approve up to 30 mg daily (taken as one 5 or 10 ... , Baclofen has an average rating of 7.0 out of 10 from a total of 435 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. Tizanidine has an average rating of 6.1 out of 10 from a total of 377 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 30% reported a negative effect., Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective. There is very limited or inconsistent data regarding the effectiveness of metaxalone, methocarbamol, chlorzoxazone, baclofen, or dantrolene compared to placebo in patients with musculoskeletal conditions., The skeletal muscle relaxants carisoprodol, chlorzoxazone, cyclobenzaprine, metaxalone, methocarbamol, and orphenadrine have been approved for treatment of musculoskeletal disorders, but not for spasticity. They constitute a heterogeneous group of medications. Cyclobenzaprine is closely related to the tricyclic antidepressants,19 carisoprodol