Methocarbamol interactions with gabapentin

Take a look at more than a dozen interactive websites that can inspire your own design. Then, walk through some steps you can take to make your site interactive. Trusted by busines...

Methocarbamol interactions with gabapentin. Using Gabapentin and Robaxin together may increase the side effects such as dizziness, drowsiness, difficulty concentrating, and confusion. Some people may find a problem in judgment, motor coordination, and impairment in thinking, especially the elderly. Try to avoid using Robaxin with alcohol during the treatment of these medications.

The following applies to the ingredients: Alprazolam (found in Xanax) and Gabapentin. Using ALPRAZolam together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.

Gabapentin is sold under the brand name Neurontin and is available as a generic product as well. (Generic medications are chemically the same as brand-name drugs but may cost less.) Gabapentin is also available as an extended-release tablet that works for a longer length of time; this is the only formulation that is approved for restless legs ...Drug interactions are reported among 1,284 peopel who take Gabapentin and Robaxin. Common interactions among females include chest pain and insomnia. Common interactions among males include drug ineffective and anxiety. ... Robaxin has active ingredients of methocarbamol. It is used in muscle spasms. Currently, eHealthMe is …Absorption. The bioavailability of carbamazepine is in the range of 75-85% of an ingested dose. 3 After one 200 mg oral extended-release dose of carbamazepine in a pharmacokinetic study, the Cmax carbamazepine was measured to be 1.9 ± 0.3 mcg/mL. The Tmax was 19 ± 7 hours. After several doses of 800 mg every 12 hours, the peak concentrations of carbamazepine were measured to be 11.0 ± 2.5 ...HYDROmorphone gabapentin. Applies to: hydromorphone and gabapentin. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or ...methocarbamol traMADol. Applies to: methocarbamol and tramadol. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.gabapentin traMADol. Applies to: gabapentin and tramadol. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.

Spotify today is introducing a new feature designed to make podcasts more interactive. The company says it’s beginning to test “Polls,” a tool that will allow listeners to engage w...Sotalol Interactions. There are 607 drugs known to interact with sotalol, along with 20 disease interactions, and 3 alcohol/food interactions.Of the total drug interactions, 228 are major, 350 are moderate, and 29 are minor.Applies to: methocarbamol. Alcohol can increase the nervous system side effects of methocarbamol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with methocarbamol.This review focuses on pre-appointment medications used to decrease fear and anxiety in dogs and cats related to veterinary visits. A review of the literature revealed data on 4 medications from 4 medication classes that have been used to ameliorate acute situational fear and anxiety in dogs and cats: gabapentin, trazodone, oral transmucosal dexmedetomidine, and alprazolam.Gabapentin was not found to interact with alcohol, i.e. did not increase blood alcohol concentration, feelings of sedation or motor impairment. Although considered to have low abuse potential in the general population, patients in opioid withdrawal, or those who abuse prescription drugs, may be at increased risk for gabapentinoid abuse or ...

Socala et al. 42 observed that CBD increased the activity of topiramate, oxcarbazepine, pregabalin, tiagabine, and gabapentin, but did not affect the anticonvulsant effect of lamotrigine and lacosamide. Increased anticonvulsant activity of AEDs was partly related to pharmacokinetic interactions with CBD because CBD increased serum and brain ...These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderatemethocarbamol gabapentin. Applies to: Robaxin (methocarbamol) and gabapentin. Using methocarbamol together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Sedation and impairment of attention, judgment, thinking, and psychomotor skills may increase. MANAGEMENT: During concomitant use of these drugs, patients should be monitored for potentially excessive or prolonged CNS and respiratory depression. Cautious dosage titration may be required, particularly at treatment initiation.Oxcarbazepine Interactions. There are 567 drugs known to interact with oxcarbazepine, along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 44 are major, 504 are moderate, and 19 are minor. ... gabapentin, clonazepam, lamotrigine, lorazepam, pregabalin, topiramate, diazepam. Images. … Robaxin, also known as methocarbamol, is a muscle relaxant medication used to treat muscle pain and tightness caused by strains, sprains, or other muscle injuries. It works by blocking nerve impulses that transmit pain signals to the brain, providing relief from muscle discomfort. Robaxin is available in the form of tablets, with commonly ...

Jonathan shuttlesworth biography.

methocarbamol gabapentin. Applies to: Robaxin (methocarbamol) and Neurontin (gabapentin) Using methocarbamol together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. There are 19 disease interactions with Tylenol with Codeine #1 (acetaminophen / codeine) which include: alcoholism. liver disease. impaired GI motility. infectious diarrhea. prematurity. acute alcohol intoxication. drug dependence. hypotension.ALPRAZolam methocarbamol. Applies to: Xanax (alprazolam) and methocarbamol. Using ALPRAZolam together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Let's review a few possible losartan interactions you should know about. 1. Medications that raise potassium levels. Potassium is an electrolyte that's commonly found in the body. Medical conditions, your diet, and even medications can cause higher potassium levels than normal. This is called hyperkalemia.Applies to: hydrocodone and gabapentin. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.

Too much acetaminophen may cause liver problems. Follow the directions exactly. Do not take more acetaminophen in a day than directed. If you do not know how much acetaminophen you can take in a day, ask your doctor or pharmacist. Some people may take up to 4,000 mg (milligrams) in a day if told to do so by the doctor.Drug interactions are reported among people who take Gabapentin and Robaxin. Common interactions among females include chest pain and insomnia. Common interactions among males include drug ineffective and anxiety. The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Robaxin together.Common interactions include bronchitis among females and arthralgia among males. The phase IV clinical study analyzes what interactions people who take Methocarbamol and Lidocaine have. It is created by eHealthMe based on reports of 304 people who take Methocarbamol and Lidocaine from the FDA, and is updated regularly.Introduction. Major depression remains a prevalent disorder that has a significant impact on the mental health of our American population. According to results from the 2012 National Survey on Drug Use and Health, 9.1% of youth (ages 12-17 years) had a major depressive episode in the past year, which is an increase in prevalence compared with 2006-11 survey results (7.9%-8.3% of youth with a ...Common interactions include bronchitis among females and arthralgia among males. The phase IV clinical study analyzes what interactions people who take Methocarbamol and Lidocaine have. It is created by eHealthMe based on reports of 304 people who take Methocarbamol and Lidocaine from the FDA, and is updated regularly.Key takeaways: Hydroxyzine (Vistaril) is a medication used for allergies, itching, and anxiety. It interacts with several medications and alcohol. Opioid pain medications and other antihistamines, such as diphenhydramine (Benadryl), interact with hydroxyzine. Combining them can cause severe drowsiness and raise the chance of accidental injuries.Star 7. Summary. Methocarbamol is a CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions. Brand Names. Robaxacet, Robaxacet-8, Robaxin, Robaxisal. Generic Name. Methocarbamol. DrugBank Accession Number. DB00423.For generations, we thought the moon was a barren rock. We were wrong. Early this week, a rover from China landed on the far side of the Moon, making it the first time humans have ...

Tolerance as well as physical and psychological dependence can develop, particularly after prolonged use of excessive dosages, and abrupt cessation and/or a reduction in dosage may precipitate withdrawal symptoms. In patients who have developed tolerance, overdosage can still produce respiratory depression and death.

The use of gabapentin is associated with increased rates of respiratory depression among patients undergoing laparoscopic surgery. When gabapentinoids are included in multimodal analgesic regimens, intraoperative opioids must be reduced, and increased vigilance for respiratory depression may be warranted, especially in elderly patients.Gabapentin can cause deficiencies in calcium as it works on the calcium channels … not on the neurotransmitter GABA (it was designed to mimic the chemical structure of gamma-aminobutyric acid). It can also cause deficiencies in vitamin D, vitamin B1, and folate. Ironically, all these nutrients help with nerve repair.Methocarbamol (Robaxin) is an oral medication used to treat muscle pain and stiffness. Learn about side effects, warnings, dosage, and more. ... Interactions that increase the risk of side effects.On the other side, such meds like Xanax can be addictive and provoke bad side effects like dizziness, drowsiness, diarrhea, vomiting and even blurred vision. CBD oil drug interactions might increase some of the side effects. That’s why dosage is key. You can use CBD oil for pets to improve bad side effects and decrease current medication …BZDs are considered controlled substances. A few examples include alprazolam (Xanax), clonazepam (Klonopin), temazepam (Restoril). Some of meclizine's side effects overlap with those of BZDs. Examples include drowsiness, headache, and vomiting. If meclizine is taken with a BZD, these side effects may intensify.propranolol methocarbamol. Applies to: propranolol and methocarbamol. Propranolol and methocarbamol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment ...constipation, loss of coordination, headache, drowsiness, and. fainting. Seek medical care or call 911 at once if you have the following serious side effects: Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;morphine gabapentin. Applies to: morphine and gabapentin. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.

Federal prison pollock.

Black outlaw mc clubs.

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. ModerateCommon interactions among females include hypoaesthesia and headache. Common interactions among males include chronic kidney disease and renal failure. The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Amoxicillin together. It is created by eHealthMe based on data from the FDA, and is updated ...Answers. IN. Inactive 17 April 2013. Methocarbamol is used in the treatment of muscle spasm; tetanus; opiate withdrawal and belongs to the drug class skeletal muscle relaxants. Gabapentin is used in the treatment of postherpetic neuralgia; restless legs syndrome; epilepsy; vulvodynia; postmenopausal symptoms (and more), and belongs to the drug ...Multimodal analgesic therapies for acute postoperative pain have become popular under the premise that combining analgesics with different mechanisms of action improves pain control when mitigating the adverse effects of individual medications. 1–3 Such analgesic therapies have been used to improve patient satisfaction and hasten …Common side effects of methocarbamol. Common side effects of methocarbamol include dizziness and sleepiness. About 1 in 10 people will have problems with one or the other. The most common side effects are: Sleepiness. Dizziness. Nausea. Indigestion. Metallic taste in the mouth.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching /swelling ...The Transportation Secretary said driver-assistance technology had 'a lot of promise,' but had to be deployed in a "responsible fashion." Jump to The way drivers interact with self...Common interactions among females include pain in extremity and osteopenia. Common interactions among males include chronic kidney disease and depression. The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Flexeril together.Answers. IN. Inactive 17 April 2013. Methocarbamol is used in the treatment of muscle spasm; tetanus; opiate withdrawal and belongs to the drug class skeletal muscle relaxants. Gabapentin is used in the treatment of postherpetic neuralgia; restless legs syndrome; epilepsy; vulvodynia; postmenopausal symptoms (and more), and belongs to the drug ...oxyCODONE methocarbamol. Applies to: oxycodone and Robaxin (methocarbamol) Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns.Lidocan Patch disease interactions. There are 5 disease interactions with Lidocan Patch (lidocaine topical) which include: teething pain. cardiovascular dysfunction. hepatic dysfunction. renal dysfunction. seizures. ….

Side Effects. Drowsiness, dizziness, lightheadedness, stomach upset, nausea / vomiting, or blurred vision may occur. If any of these effects last or get worse, tell your doctor or pharmacist ... Common interactions among females include dizziness and diarrhoea. Common interactions among males include drug dependence and drug ineffective. The phase IV clinical study analyzes what interactions people have when they take Baclofen and Methocarbamol together. It is created by eHealthMe based on data from the FDA, and is updated regularly.According to 1-800-PetMeds, common gabapentin doses for dogs are 1.4 mg per pound once a day for chronic pain or 4.5 to 13.5 mg per pound every 8-12 hours for seizures. But rely on your vet for the proper dosage for your dog. It can vary based on his weight, other health concerns, and what it's being used for.ALPRAZolam methocarbamol. Applies to: Xanax (alprazolam) and methocarbamol. Using ALPRAZolam together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Answer. There is no known interaction between gabapentin and NyQuil. However, it's important to note that NyQuil contains several active ingredients, including doxylamine, which is a sedating antihistamine. Gabapentin is well known to have sedative side effects, especially at higher doses. Therefore, taking NyQuil with gabapentin can increase ...Drug interactions are reported among 314 peopel who take Methocarbamol and Atorvastatin calcium. Common interactions among females include nasopharyngitis and dysphagia. Common interactions among males include chronic kidney disease and nausea. ... Gabapentin, Methocarbamol, Lovenox, Acetaminophen, Tamsulosin, Indomethacin, Lisinopril - 13 ...methocarbamol gabapentin. Applies to: Robaxin (methocarbamol) and Neurontin (gabapentin) Using methocarbamol together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Find patient medical information for Methocarbamol-ASA oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.Summary: Drug interactions are reported among people who take Methocarbamol and Advil. Common interactions among females include oral pain and arthropathy. Common interactions among males include dyspnoea and malaise. The phase IV clinical study analyzes what interactions people have when they take Methocarbamol and Advil together. Methocarbamol interactions with gabapentin, Lidocan Patch disease interactions. There are 5 disease interactions with Lidocan Patch (lidocaine topical) which include: teething pain. cardiovascular dysfunction. hepatic dysfunction. renal dysfunction. seizures., Gabapentin is sold under the brand name Neurontin and is available as a generic product as well. (Generic medications are chemically the same as brand-name drugs but may cost less.) Gabapentin is also available as an extended-release tablet that works for a longer length of time; this is the only formulation that is approved for restless legs ..., There are 9 disease interactions with Contrave (bupropion / naltrexone) which include: suicidality. seizure disorders. hepatic dysfunction. angle closure glaucoma. liver disease. mixed/manic episode. renal dysfunction. hepatic/renal dysfunction., Applies to: methocarbamol. Alcohol can increase the nervous system side effects of methocarbamol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with methocarbamol., Applies to: Robaxin (methocarbamol) Alcohol can increase the nervous system side effects of methocarbamol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with methocarbamol., Apr 15, 2024 · Methocarbamol is taken by mouth, typically 3 or 4 times daily. It's also available as an injection that's given into the muscles or through the veins, typically in a hospital setting. Side effects of methocarbamol include dizziness, drowsiness, and blurry vision. Reviewed by: Robert Chad Hakim, PharmD, BCCCP. Allison Gourley, PharmD. , cyclobenzaprine gabapentin. Applies to: Flexeril (cyclobenzaprine) and gabapentin. Using cyclobenzaprine together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Applies to: gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose ..., At its essence, social interaction is defined as the manner in which people talk to and interact with one another. Social interaction is dependent upon the societal structure in wh..., Store your methocarbamol tablets at room temperature, 68 to 77F (20 to 25C). 6. Response and effectiveness. Methocarbamol starts working in about 30 minutes and its full effects are seen within 2 hours. Methocarbamol is relatively short-acting and needs to be taken three to four times a day as directed by a doctor. 7. Interactions, methocarbamol food. Applies to: methocarbamol. Alcohol can increase the nervous system side effects of methocarbamol such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with methocarbamol., Gabapentin works in the brain to prevent seizures and relieve pain for certain conditions in the nervous system. It is not used for routine pain caused by minor injuries or arthritis. Gabapentin is an anticonvulsant. This medicine is available only with your doctor's prescription. This product is available in the following dosage forms: Capsule., Methocarbamol Interactions With Gabapentin. When considering the potential interactions between Methocarbamol and Gabapentin, it's crucial to know how they may affect each other when used together. Here are some key points to keep in mind: Sedation: Methocarbamol and Gabapentin can cause drowsiness and central nervous system depression. They ..., When gabapentin and methocarbamol are used together, there is a potential for drug interactions to occur. For instance, the sedative effects of methocarbamol may be enhanced by the presence of gabapentin in the system, leading to increased sedation and lethargy in the dog., Benefits and Uses of Baclofen. Baclofen offers a range of benefits and is commonly used to alleviate muscle spasms and muscle stiffness caused by various medical conditions. The primary benefit of Baclofen is its ability to relax muscles, reducing excessive muscle contractions and the associated pain and discomfort., Dantrolene. Dantrolene (Dantrium) is a skeletal muscle relaxer used to treat muscle spasms caused by spinal cord injury, stroke, cerebral palsy, or MS. It works by acting directly on the skeletal ..., Applies to: gabapentin and Zanaflex (tizanidine) Using tiZANidine together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of ..., Methocarbamol (Robaxin-V) Metoclopramide (Reglan) Metronidazole (Flagyl) Milbemycin Oxime. ... Brand Name: Neurontin. Available in 100 mg, 300 mg, and 400 mg capsules; 600 mg and 800 mg tablets; and oral solution (some products not appropriate for dogs) ... Interactions with Other Drugs. For chronic pain relief, gabapentin is best started in ..., HYDROmorphone gabapentin. Applies to: hydromorphone and gabapentin. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any …, hydrOXYzine methocarbamol. Applies to: hydroxyzine and Robaxin (methocarbamol) Using hydrOXYzine together with methocarbamol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination., Answer. There is no known interaction between gabapentin and NyQuil. However, it's important to note that NyQuil contains several active ingredients, including doxylamine, which is a sedating antihistamine. Gabapentin is well known to have sedative side effects, especially at higher doses. Therefore, taking NyQuil with gabapentin can increase ..., Taking Benadryl and Robaxin will likely result in additive side effects and their use together should be limited in most situations. Robaxin has a relatively short half-life and is eliminated from the body quickly. It would be prudent to wait at least 12 hours between Robaxin and Benadryl to avoid additive side effects as much as possible., These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate, The potential side effects of Methocarbamol and Gabapentin in dogs include drowsiness, lethargy, ataxia (loss of motor coordination), vomiting, diarrhea, and loss of appetite. These side effects are usually mild and can be managed with proper dosage adjustments or by discontinuing the medication. However, in rare cases, overdose or toxicity can ..., Applies to: gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose ..., Baclofen Interactions. There are 365 drugs known to interact with baclofen, along with 4 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 27 are major, 337 are moderate, and 1 is minor., More about Methocarbamol. Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported ..., These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate, 1. Introduction. Myasthenia gravis (MG) is the most common type of neuromuscular transmission disease and is caused by autoantibodies against acetylcholine receptors (AChRs) in the neuromuscular junction or their adjacent proteins. The incidence and prevalence rates of MG are estimated at 0.3-2.8 and 5.35-35 per 100,000, respectively [ 1 ]., Applies to: Morphine Sulfate ER (morphine) and gabapentin. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression such as gabapentin can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns., Answers. Essd1; These 2 medications can not be compared they are completely different it would be like the difference in an apple and a pear. The best you can do is check with your doctor about how you should take them or if you should take together the Robaxin is more just a muscle relaxant and Gabapentin is used for many different things and ..., Diclofenac (Cambia, Cataflam) is a nonsteroidal anti-inflammatory drug (NSAID). It can interact with several other medications and alcohol. Common diclofenac interactions include aspirin, blood thinners, and methotrexate. The main risks with many interactions are stomach bleeding and kidney damage. Topical forms of diclofenac, like Voltaren gel ..., These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication. Major: Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. Moderate