Can you take nyquil with gabapentin

Bactrim disease interactions. There are 12 disease interactions with Bactrim (sulfamethoxazole / trimethoprim) which include: colitis. hematologic toxicity. hypersensitivity reactions. liver disease. porphyria. renal dysfunction. folate deficiency.

Can you take nyquil with gabapentin. Answer. There is no known interaction between NyQuil and Keflex (cephalexin). They are considered safe to take together. In fact, NyQuil is safe to take with the vast majority of antibiotics, certainly with most of the common ones you'd see used for an ear infection (e.g., amoxicillin, azithromycin, amoxicillin; clavulanic acid, Bactrim etc ...

Carbidopa/levodopa disease interactions. There are 12 disease interactions with carbidopa / levodopa which include: glaucoma. cardiac disease. hypotension. neuroleptic malignant syndrome. psychoses/depression. psychosis. glaucoma.

Mar 12, 2023 · There are certain drugs that should be avoided when taking benzonatate due to their potential interactions. Examples of such drugs include: Alcohol: Mixing alcohol with benzonatate can lead to increased drowsiness and may exacerbate the medication's sedative effects. It is advisable to avoid consuming alcohol while taking benzonatate. Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure. Pharmacy Pharmacy online online Pharmacy Pharmacy Pharmacy Pharmacy The typical dose for adults is 500mg of amoxicillin every 8 hours, or 875mg every 12 hours for more severe infections. For children, the dosage is determined by their weight and is usually calculated as 20-45mg per kilogram of body weight per day, divided into two or three doses.There are 8 disease interactions with Vicks Nyquil Cough (dextromethorphan / doxylamine) which include: depression. anticholinergic effects. asthma/COPD. cardiovascular. renal/liver disease. glaucoma. liver disease. resp depression.Boeing has rolled out the first 737 MAX 10, which is the company's longest-ever 737. But the roll-out comes as the family of jets remains grounded pending re-certification by globa...Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Key points. There are several safe cold/flu medications safe with Celexa (citalopram), and others you should use caution with. Safe medications include Tylenol (acetaminophen), antihistamines, and Mucinex. Dextromethorphan, NSAIDs (e.g. ibuprofen), and Sudafed should be used cautiously. Thanks so much for reaching out!5. St. John's Wort. St. John's wort interacts with a variety of medications, according to the Mayo Clinic. That includes antidepressants, birth control pills, cyclosporine, HIV drugs and blood thinners, Trejo says, so make sure to talk with your doctor before you drink teas with St. John's wort.Key points. Combining NyQuil and gabapentin can increase the risk of certain side effects, such as dizziness, drowsiness, and impaired coordination, due to the sedating antihistamine doxylamine in NyQuil and the dose-dependent sedative effects of gabapentin.Can you take gabapentin and dayquil? Updated: 9/7/2023. Wiki User. ∙ 9y ago. Best Answer. It is advisable to NOT. Nyquil contains 10% alcohol in it. Wiki User. ∙ 12y ago.An armada of tiny lenders are needed to help protect small businesses and millions of jobs. In Marfa, Texas, you’re more likely to meet a hipster tourist from Brooklyn than a cowbo... Applies to: Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine) and gabapentin. Using dextromethorphan together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Although most people would not get noticeable drowsiness from 100 mg, the tolerance varies greatly among people. Nyquil will add to the drowsiness. Believe it is best for you to wait till the weekend to try the combination .For oral dosage forms (capsules, liquid, and tablets): For epilepsy: Adults and children 12 years of age and older—At first, 300 milligrams (mg) 3 times per day. Your doctor may adjust your dose as needed and tolerated. However, the dose is usually not more than 1800 mg per day (600 mg 3 times per day). Children 3 to 11 years of age—Dose is ...An armada of tiny lenders are needed to help protect small businesses and millions of jobs. In Marfa, Texas, you’re more likely to meet a hipster tourist from Brooklyn than a cowbo...Enalapril disease interactions. There are 7 disease interactions with enalapril which include: angioedema. bone marrow suppression. hemodialysis. hyperkalemia. hypotension. liver disease. renal dysfunction.ZzzQuil (diphenhydramine) Edit list (add/remove drugs) Consumer. Professional. Interactions between your drugs. Moderate. diphenhydrAMINE gabapentin. Applies to: …Answer. There is no known interaction between NyQuil and Keflex (cephalexin). They are considered safe to take together. In fact, NyQuil is safe to take with the vast majority of antibiotics, certainly with most of the common ones you'd see used for an ear infection (e.g., amoxicillin, azithromycin, amoxicillin; clavulanic acid, Bactrim etc ...

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Original formula NyQuil liquid cold and flu medicine contains 25 percent alcohol by volume, according to the State University of New York Potsdam. The percentage of alcohol is not ...Oct 11, 2022 · The short answer is yes, you can take Nyquil with muscle relaxers. However, there are a few things you should keep in mind before doing so. Muscle relaxers are a type of medication that work by blocking pain signals from the nervous system. They’re typically used to treat conditions like back pain, neck pain, and muscle spasms. 6. Alcohol. Alcohol can cause dizziness, making motion sickness symptoms worse. So, drinking alcohol with Dramamine won’t do you any favors. What’s more, combining Dramamine with alcohol can increase the risk of drowsiness. The safest way to handle this interaction is to avoid alcohol with Dramamine. Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose of gabapentin, and avoid ...Ramipril disease interactions. There are 7 disease interactions with ramipril which include: angioedema. bone marrow suppression. hemodialysis. hyperkalemia. hypotension. liver disease. renal dysfunction.

If you are prescribed antibiotics or antifungals for an infection, be sure to let your doctor know if you’re also taking warfarin. 5. Some Asthma Medications. If you have atrial fibrillation, it’s important to be cautious with certain prescription asthma medications. Asthma drugs like bronchodilators and oral steroids can be risky for ...One ingredient in this product is acetaminophen.Taking too much acetaminophen may cause serious (possibly fatal) liver disease.Adults should not take more than 4000 milligrams (4 grams) of ...Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.A new book, The Waste of a Nation, analyses the history and evolution of the crisis in India. India seems to be drowning in garbage. From Delhi to Mumbai to Bengaluru, mini hills o...There are 9 disease interactions with Contrave (bupropion / naltrexone) which include: suicidality. seizure disorders. hepatic dysfunction. angle closure glaucoma. liver disease. mixed/manic episode. renal dysfunction. hepatic/renal dysfunction.Yes, a ketogenic diet while on medication is possible. While some medicines interfere with ketosis, you still benefit from keto’s health benefits. Your need for medication may lessen as your body responds and adapts to the keto diet. Don’t stop medication or lower dosages without consulting with your doctor. 9.Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose of gabapentin, and avoid ...Amoxicillin is available in doses of 250 mg, 500 mg and 1 g. These are administered in different combinations depending upon the clinical condition. Amoxicillin is used as a 500 mg oral or intravenous drug. In treating simple pneumonias, amoxicillin is prescribed as a 500 mg oral medication given 2 to 3 times a day for a variable duration of time …Zyrtec (cetirizine) Edit list (add/remove drugs) Consumer. Professional. Interactions between your drugs. Moderate. gabapentin cetirizine. Applies to: gabapentin and Zyrtec … Lamotrigine Interactions. There are 285 drugs known to interact with lamotrigine, along with 8 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 9 are major, 264 are moderate, and 12 are minor.

The other medications listed here may not raise tizanidine levels as much. But you should talk to your healthcare provider before taking them. They can help you weigh the risks and benefits. They might consider lowering your tizanidine dose. Or they may just ask you to watch out for tizanidine side effects. 2. Birth control pills

From military discounts to projected traffic fatalities, and from holiday freebies to the surprising number of towns bickering over which is truly the birthplace of Memorial Day, h...One ingredient in this product is acetaminophen.Taking too much acetaminophen may cause serious (possibly fatal) liver disease.Adults should not take more than 4000 milligrams (4 grams) of ...Clomipramine disease interactions. There are 22 disease interactions with clomipramine which include: anticholinergic effects. cardiovascular disease. pheochromocytoma. acute myocardial infarction recovery. cardiovascular disease. seizure disorders. adrenal tumors.Take magnesium citrate the evening before the colonoscopy, as directed. Ensure to follow the recommended dosage and consume enough clear liquids. Bisacodyl Tablets. Bisacodyl is an over-the-counter stimulant laxative, often sold in tablet form. It works by directly stimulating the intestines, promoting bowel movements.Wrapping Up. Nyquil is an effective medication for treating cold and flu symptoms, but it is not an effective choice for treating allergies. While it can help to relieve some symptoms associated with allergies, it is not a long-term solution. It is important to accurately diagnose your allergies so you can get the treatment that targets the ...There are 8 disease interactions with Vicks Nyquil Cough (dextromethorphan / doxylamine) which include: depression. anticholinergic effects. asthma/COPD. cardiovascular. renal/liver disease. glaucoma. liver disease. resp depression.gabapentin; hydrochlorothiazide; levothyroxine; Lipitor (atorvastatin) lisinopril; losartan; Lyrica (pregabalin) metformin; Nexium (esomeprazole) omeprazole; oxycodone; ... Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction ...From military discounts to projected traffic fatalities, and from holiday freebies to the surprising number of towns bickering over which is truly the birthplace of Memorial Day, h...Mar 12, 2023 · There are certain drugs that should be avoided when taking benzonatate due to their potential interactions. Examples of such drugs include: Alcohol: Mixing alcohol with benzonatate can lead to increased drowsiness and may exacerbate the medication's sedative effects. It is advisable to avoid consuming alcohol while taking benzonatate. Oct 20, 2022 · Their symptoms can often be relieved with over-the-counter medications. Flu medications, like Tamiflu (oseltamivir), shouldn’t be used to treat COVID-19. And although there are benefits to getting the flu shot, it can’t protect you from COVID-19. Veklury (remdesivir) and Olumiant (baricitinib) are two FDA-approved medications for COVID-19.

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Hi.Welcome to just answer.I am caring doc.I can help you today.Respected customer, you can take them,but keep in mind using Nyquil together with Gabapentin may cause excessive drowsiness.You should avoid or limit the use of alcohol while being treated with these medication together. Also avoid activities requiring mental alertness such as ...Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. ... gabapentin, clonazepam, lamotrigine, lorazepam, pregabalin, topiramate, diazepam. Images. Vimpat lacosamide 50 mg (SP 50) View all images.Prazosin Interactions. There are 261 drugs known to interact with prazosin, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 8 are major, 252 are moderate, and 1 is minor.Key points. Combining NyQuil and gabapentin can increase the risk of certain side effects, such as dizziness, drowsiness, and impaired coordination, due to the sedating antihistamine doxylamine in NyQuil and the dose-dependent sedative effects of gabapentin.Includes amlodipine, gabapentin, lisinopril. Skip to main ... assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring ... , diphenhydramine, Benadryl, guaifenesin, dextromethorphan, Mucinex, chlorpheniramine, Promethazine DM, Vicks NyQuil Cold & Flu Nighttime Relief ... Valacyclovir Interactions. There are 67 drugs known to interact with valacyclovir, along with 4 disease interactions. Of the total drug interactions, 23 are major, 38 are moderate, and 6 are minor. Call your doctor or 911 if you think you may have a medical emergency. can i take nyquil with either gabapentin or cyclobenzaprine before going to sleep? i have no plans tomorrow that drowsiness will effect.: It's ok.: Only take as recommended and nothing more. Drug interactions are reported among people who take Ambien and Nyquil. Common interactions among females include mononucleosis syndrome and multiple sclerosis relapse. Common interactions among males include dizziness and middle insomnia. The phase IV clinical study analyzes what interactions people have when they take Ambien and Nyquil ... Beginners often ask if credit cards are worth the annual fee. In the case of the Chase Sapphire Preferred, the answer is almost always yes. Editor’s note: This is a recurring post,...Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Older adults who take gabapentin also are at higher risk of breathing problems. Because gabapentin can enhance the psychological effect of opioids, it has the potential to be abused and has contributed to drug overdose deaths. Drugs such as gabapentin have been linked in rare cases to an increased risk of suicidal thoughts or … ….

Carry all of your medication — even vitamins and supplements — in their original, clearly marked containers or packaging in a clear plastic bag in carry on luggage. Make sure the name on the ...Coricidin HBP Cough & Cold disease interactions. There are 4 disease interactions with Coricidin HBP Cough & Cold (chlorpheniramine / dextromethorphan) which include: anticholinergic effects. asthma/COPD. cardiovascular. renal/liver disease.Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you …Gabapentin is an anticonvulsant medication that works by decreasing abnormal excitement in the brain and changing the way the body senses pain, according to MedlinePlus. Gabapentin...If you need to take both NyQuil and Delsym for your symptoms, it is important to separate the doses by the appropriate amount of time to avoid the risk of double dosing. So, if you take NyQuil first, you can safely take Delsym after 4 to 6 hours. If you take a 12-hour version of Delsym first, you should wait at least that amount of time before ...Gabapentin is an anticonvulsant medication that works by decreasing abnormal excitement in the brain and changing the way the body senses pain, according to MedlinePlus. Gabapentin...Yes, a ketogenic diet while on medication is possible. While some medicines interfere with ketosis, you still benefit from keto’s health benefits. Your need for medication may lessen as your body responds and adapts to the keto diet. Don’t stop medication or lower dosages without consulting with your doctor. 9.Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Last updated on Feb 14, 2024. Yes, you can overdose on Nyquil if you take more than recommended, give a child more than is recommended, or you give Nyquil to a child who is under the age of 6 years. Nyquil contains acetaminophen (relieves pain and fever), doxylamine (an antihistamine that will dry up nasal secretions but can cause drowsiness ... Can you take nyquil with gabapentin, gabapentin; hydrochlorothiazide; ibuprofen; levothyroxine; lisinopril; losartan; magnesium oxide; melatonin; metformin; metoprolol; Metoprolol Succinate ER (metoprolol) omeprazole; ... Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No ..., Cautions with other medicines. Some medicines may affect how gabapentin works or increase the chance of you having side effects. Antacids can reduce the amount of gabapentin that the body takes in so it does not work as well. To stop this happening, if you need to take an antacid, take it at least 2 hours before or after your dose of gabapentin., Alcohol in Nyquil: Nyquil is 25% alcohol by volume - that is 50 proof. Table wine is usually 12% by volume. Hard liquor is usually 80 or 100 proof (40-50%). Created for people with ongoing healthcare needs but benefits everyone. Learn how we can help., Taking steroid drugs in any form – orally, topically, through an inhaler or IV – can worsen glaucoma for these patients. Steroids applied closest to the eye carry the highest risk. Drugs taken by mouth or through an IV enter the eye through the bloodstream — about as close to the eye as you can get. But skin creams and inhalers are also ..., Naltrexone Interactions. There are 338 drugs known to interact with naltrexone, along with 2 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 34 are major, and 304 are moderate. , Avoid taking an antacid within 2 hours before you take gabapentin. Do not drink alcohol. Dangerous side effects could occur. Gabapentin side effects. Get emergency medical help if you have signs of an allergic reaction to gabapentin: hives, difficult breathing, swelling of your face, lips, tongue, or throat., The other medications listed here may not raise tizanidine levels as much. But you should talk to your healthcare provider before taking them. They can help you weigh the risks and benefits. They might consider lowering your tizanidine dose. Or they may just ask you to watch out for tizanidine side effects. 2. Birth control pills, gabapentin; hydroxyzine; ibuprofen; levothyroxine; lisinopril; magnesium oxide; melatonin; metformin; Mucinex (guaifenesin) omeprazole; ondansetron; pantoprazole; prednisone; tramadol; trazodone; Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Zyrtec (cetirizine) Pepto-Bismol disease ..., Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. Unknown: No interaction information available. Further information. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances., Applies to: gabapentin. Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose ... , There are 8 disease interactions with Vicks Nyquil Cough (dextromethorphan / doxylamine) which include: depression. anticholinergic effects. asthma/COPD. cardiovascular. renal/liver disease. glaucoma. liver disease. resp depression., Archer Aviation, the electric aircraft startup that recently announced a deal to go public via a merger with a blank-check company, plans to launch a network of its urban air taxis..., First, alcohol can cause or worsen ED. If you’re taking sildenafil to help with ED, alcohol may counteract its effects. Second, alcohol widens blood vessels in the body, like sildenafil. So there’s a risk of low blood pressure when combining the two. And, finally, alcohol can worsen other sildenafil side effects., normal time you take your meds, make sure to pack that single dose in. your carry on. I also wanted to comment on this, from Letizia. ALL of your meds should be in your carry on or your personal item when flying. You should NEVER put prescription meds in your checked bags, in case they are delayed or lost., Yes, a ketogenic diet while on medication is possible. While some medicines interfere with ketosis, you still benefit from keto’s health benefits. Your need for medication may lessen as your body responds and adapts to the keto diet. Don’t stop medication or lower dosages without consulting with your doctor. 9., Sep 21, 2022 · Key takeaways: Tramadol (Ultram, ConZip, Qdolo) is an opioid medication used to treat pain. It has many possible drug interactions, including some antidepressants, antibiotics, and diuretics. Some tramadol interactions raise the risk of side effects of tramadol. Examples include sleepiness, an increased risk of seizures, or serotonin syndrome. , He currently takes 300mg Gabapentin before bed for restless leg syndrome, and he's coming down with a cold. I'm wondering if it would be okay for him to take a nyquil tonight with his Gabapentin? Or just stick with dayquil? He also takes (prescribed) Effexor, Nexium, and Allegra in the morning. No known drug allergies., normal time you take your meds, make sure to pack that single dose in. your carry on. I also wanted to comment on this, from Letizia. ALL of your meds should be in your carry on or your personal item when flying. You should NEVER put prescription meds in your checked bags, in case they are delayed or lost., Lamotrigine Interactions. There are 285 drugs known to interact with lamotrigine, along with 8 disease interactions, and 1 alcohol/food interaction.Of the total drug interactions, 9 are major, 264 are moderate, and 12 are minor., 5. St. John's Wort. St. John's wort interacts with a variety of medications, according to the Mayo Clinic. That includes antidepressants, birth control pills, cyclosporine, HIV drugs and blood thinners, Trejo says, so make sure to talk with your doctor before you drink teas with St. John's wort., Buy Prednisone Online Prednisone 40, 20, 10, 5 mg $0.29 Per Pill Active Ingredient: Prednisone Prednisone is able to help during any severe disease. Prednisone is a commonly prescribed medication that belongs to a class of drugs known as corticosteroids. It is primarily used for its potent anti-inflammatory and immunosuppressive properties., • Check this list before taking any over the counter medicine and take it as directed on the package • (just make sure the You may use the store-brand product instead of the brand names listed below active ingredients list on the box matches) • This list does not include every over the counter product., There are 124 drugs known to interact with Tylenol Arthritis Pain (acetaminophen), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 8 are major, 80 are moderate, and 36 are minor., This can include diuretics, diabetes medications, and lithium. Interactions can result in low blood pressure, low blood sugar, and other signs and symptoms. Your healthcare provider and pharmacist can check for potential interactions. This can ensure you’re taking lisinopril with other medications safely., Answer. There are no drug interactions between venlafaxine, gabapentin and most over the counter sleep aids. These products include Benadryl (diphenhydramine) and Unisom (doxylamine). Nyquil, another common product that causes sedation, contains doxylamine as well. If you have another drug in mind, let us know and we can look into …, There are 124 drugs known to interact with Tylenol Arthritis Pain (acetaminophen), along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 8 are major, 80 are moderate, and 36 are minor., 4. Bottom Line. Gabapentin may be used in the treatment of partial-onset seizures and nerve pain but is likely to cause dizziness or drowsiness. Gabapentin enacarbil (brand name Horizant), a prodrug of gabapentin that can be taken once daily, may be used in the treatment of RLS and postherpetic neuralgia. 5., Changing up how much vitamin K you’re getting each day can prevent warfarin from doing its job. Green tea also contains some vitamin K, so it’s best to choose another option, like black tea ..., There are 602 drugs known to interact with Vicks NyQuil Severe Cold & Flu (acetaminophen / dextromethorphan / doxylamine / phenylephrine), along with 15 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 97 are major, 490 are moderate, and 15 are minor., The phase IV clinical study analyzes what interactions people who take Tizanidine hydrochloride and Nyquil have. It is created by eHealthMe based on reports of 6 people who take Tizanidine hydrochloride and Nyquil from the FDA, and is updated regularly. You may use the study as a second opinion to make health care decisions., Taking steroid drugs in any form – orally, topically, through an inhaler or IV – can worsen glaucoma for these patients. Steroids applied closest to the eye carry the highest risk. Drugs taken by mouth or through an IV enter the eye through the bloodstream — about as close to the eye as you can get. But skin creams and inhalers are also ..., Xarelto disease interactions. There are 6 disease interactions with Xarelto (rivaroxaban) which include: bleeding. valvular heart disease. antiphospholipid syndrome. hepatic impairment. renal disease. unstable blood pressure. , Doxycycline Interactions. There are 207 drugs known to interact with doxycycline, along with 3 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 22 are major, 180 are moderate, and 5 are minor.